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SMAD4-dependent Barrier constrains Prostate Cancer Growth and Metastatic Progression

This model-informed progression analysis, together with genetic, functional and translational studies, established SMAD4 as a key regulator of PCA progression in mice and humans. This work led to the development of a clinical test enabling stratification of men with prostate cancer into benign and aggressive groups.

Source: SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

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