SMAD4-Dependent Barrier Constrains Prostate Cancer Growth and Metastatic Progression

This model-informed progression analysis, together with genetic, functional and translational studies, established SMAD4 as a key regulator of PCA progression in mice and humans. This work led to the development of a clinical test enabling stratification of men with prostate cancer into benign and aggressive groups.

Read the Abstract

Download the PDF

Get Insights From Ron

Sign up for the latest news and updates from Ron DePinho, MD