News

Insights from Ron

These posts reflect my experience as a research scientist and the founder of numerous biotechnology companies. They include insights into pressing scientific problems, such as combating SARS-Cov-2. I write here about the significant after-effects of COVID-19 on clinical research participation and a rise of pulmonary fibrosis. A year-end roundup of the year’s most exciting research is a popular feature – the 2020 roundup will appear in January. This year, I also offer a challenge, comparing our current moment to the Sputnik Moment in 1957, with its major shifts in science, education, and social change.

Be sure to visit our other Media topics, such as the Biotechnology Entrepreneurship, Leadership Series, Features, and Ron in the News.

Insights from Ron

Opportunity in the Biomedical Roller Coaster

Even in this market meltdown, seasoned biotech innovators with decades of experience know that strong novel science in the hands …

Read More →
Insights from Ron

The Battle for Foundational Research Funding

Twentieth-century health activist Mary Lasker, who devoted her life to securing greater research funding for cancer, is quoted as saying: …

Read More →
Insights from Ron

Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer

Inactivation of the adenomatous polyposis coli (APC) is common across many cancer types and serves as a critical initiating event …

Read More →
Graphic depiction of roles of oncogenic KRAS and intratumoral fungi in promoting immune-modulating cytokine IL33 in pancreas cancer.
Insights from Ron

Fungal Mycobiome Drives IL-33 Secretion and Type 2 Immunity in Pancreatic Cancer

Paradigmatic work from PJ Dey’s Lab reveals the co-conspiratory roles of oncogenic KRAS and intratumoral fungi in promoting immune modulating …

Read More →
Insights from Ron

2021 Cancer Highlights

2021 marked the 20th anniversary of the first human genome draft sequence, which led to such revolutionary landmarks as The …

Read More →
Ron DePinho MD, on Telomeres in Cancer Aging
Insights from Ron

Alzheimer’s Disease Research Makes a Paradigm Shift

In this study, we observed that Tert haploinsufficiency affected the expression of genes integral to AD pathogenesis and that neurons …

Read More →

Get Insights From Ron

Sign up for the latest news and updates from Ron DePinho, MD