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Insights from Ron
These posts reflect my experience as a research scientist and the founder of numerous biotechnology companies. They include insights into pressing scientific problems, such as combating SARS-Cov-2. I write here about the significant after-effects of COVID-19 on clinical research participation and a rise of pulmonary fibrosis. A year-end roundup of the year’s most exciting research is a popular feature – the 2020 roundup will appear in January. This year, I also offer a challenge, comparing our current moment to the Sputnik Moment in 1957, with its major shifts in science, education, and social change.
Be sure to visit our other Media topics, such as the Biotechnology Entrepreneurship, Leadership Series, Features, and Ron in the News.
2022 Cancer Highlights
The year 2022 marked another major step in the quest to towards making cancer history. Below are several highlights among …
Targeting T cell Checkpoints and Myeloid Suppressors is an Effective Immunotherapy in Pancreas Cancer
Pat Gulhati1and Ronald DePinho2 1Department of Medical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA. 1Department …
Opportunity in the Biomedical Roller Coaster
Even in this market meltdown, seasoned biotech innovators with decades of experience know that strong novel science in the hands …
The Battle for Foundational Research Funding
Twentieth-century health activist Mary Lasker, who devoted her life to securing greater research funding for cancer, is quoted as saying: …
Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
Inactivation of the adenomatous polyposis coli (APC) is common across many cancer types and serves as a critical initiating event …
Fungal Mycobiome Drives IL-33 Secretion and Type 2 Immunity in Pancreatic Cancer
Paradigmatic work from PJ Dey’s Lab reveals the co-conspiratory roles of oncogenic KRAS and intratumoral fungi in promoting immune modulating …
