Telomere Dysfunction induces Metabolic and Mitochondrial Compromise

This study demonstrated that telomere dysfunction activates p53, which in turn binds and represses PGC-1α and PGC-1β promoters, thereby establishing a direct link between telomere and mitochondrial biology.
Read the Abstract

Download the PDF

Get Insights From Ron

Sign up for the latest news and updates from Ron DePinho, MD