Ron

The Challenging Landscape of Cancer and Aging: Charting a Way Forward

Earlier this month, I had the privilege of giving two scientific talks: one at a Grand Rounds lecture hosted by NCI’s Center for Cancer Research, and a second held at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University. Both talks focused on my research and observations on the dynamic interplay between cancer and

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Brain Cancer Patients are the First to Benefit from a Historic $100 million Mission to Defeat Brain Cancer

Australians with brain cancer – and all of those who are unknowingly at risk from this nearly always terminal disease – will benefit from an unprecedented initial donation of $10 million by the Minderoo Foundation. The seed funding will be used to develop an innovative “road map” that aims to double survival rates in patients

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Legal Action Study underway and calls for Age of Tobacco Purchases to be raised to 21

In a bid to prevent, and compensate, Australian smokers from extreme and unnecessary suffering and death, the Minderoo Foundation, has called on the Federal and State Governments to stop young people from supporting Big Tobacco companies until they are at least 21. The Foundation Chairman and co-founder, Mr Andrew Forrest AO with his wife Nicola,

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NIH Budget Cuts will Jeopardize American’s Leadership in Medical Research

In the last 10 years, remarkable advances have been made in how we fight cancer, work that was made possible by our nation’s support of biomedical research, largely through the National Institutes of Health. One of the most powerful new tools in our arsenal is cancer immunotherapy, which reawakens the body’s own immune system. Immunotherapy

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Synthetic Essentiality: Targeting Tumor Suppressor Deficiencies in Cancer

In this review, we summarize recent work exploring a novel conceptual approach termed “synthetic essentiality” as a means for targeting specific tumor suppressor gene deficiencies in cancer. With the aid of extensive publically available cancer genome and clinical databases, “synthetic essentiality” could be utilized to identify synthetic essential genes, which might be occasionally deleted in

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