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Opportunity in the Biomedical Roller Coaster

Even in this market meltdown, seasoned biotech innovators with decades of experience know that strong novel science in the hands …

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The Battle for Foundational Research Funding

Twentieth-century health activist Mary Lasker, who devoted her life to securing greater research funding for cancer, is quoted as saying: …

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Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer

Inactivation of the adenomatous polyposis coli (APC) is common across many cancer types and serves as a critical initiating event …

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Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer

Inactivation of the adenomatous polyposis coli (APC) is common across many cancer types and serves as a critical initiating event …

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Graphic depiction of roles of oncogenic KRAS and intratumoral fungi in promoting immune-modulating cytokine IL33 in pancreas cancer.

Fungal Mycobiome Drives IL-33 Secretion and Type 2 Immunity in Pancreatic Cancer

Paradigmatic work from PJ Dey’s Lab reveals the co-conspiratory roles of oncogenic KRAS and intratumoral fungi in promoting immune modulating …

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Ron DePinho MD, on Telomeres in Cancer Aging

Fungal Mycobiome Drives IL-33 Secretion and Type 2 Immunity in Pancreatic Cancer

TH2 cells and innate lymphoid cells 2 (ILC2) can stimulate tumor growth by secreting pro-tumorigenic cytokines such as interleukin-4 (IL-4), …

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