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Insights from Ron

“Anyone who has never made a mistake has never tried anything new.”

Albert Einstein

Insights from Ron

Opportunity in the Biomedical Roller Coaster

Even in this market meltdown, seasoned biotech innovators with decades of experience know that strong novel science in the hands …

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Insights from Ron

The Battle for Foundational Research Funding

Twentieth-century health activist Mary Lasker, who devoted her life to securing greater research funding for cancer, is quoted as saying: …

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Insights from Ron

Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer

Inactivation of the adenomatous polyposis coli (APC) is common across many cancer types and serves as a critical initiating event …

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Graphic depiction of roles of oncogenic KRAS and intratumoral fungi in promoting immune-modulating cytokine IL33 in pancreas cancer. Insights from Ron

Fungal Mycobiome Drives IL-33 Secretion and Type 2 Immunity in Pancreatic Cancer

Paradigmatic work from PJ Dey’s Lab reveals the co-conspiratory roles of oncogenic KRAS and intratumoral fungi in promoting immune modulating …

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Insights from Ron

2021 Cancer Highlights

2021 marked the 20th anniversary of the first human genome draft sequence, which led to such revolutionary landmarks as The …

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Ron DePinho MD, on Telomeres in Cancer Aging Insights from Ron

Alzheimer’s Disease Research Makes a Paradigm Shift

In this study, we observed that Tert haploinsufficiency affected the expression of genes integral to AD pathogenesis and that neurons …

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