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Immune cells enables escape from oncogenic KRAS dependency in pancreatic cancer

Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer. Authors: Pingping Hou, Avnish Kapoor, Qiang Zhang, Jiexi Li, Chang-Jiun Wu, Jun Li, Zhengdao Lan, Ming Tang, Xingdi Ma, Jeffrey J Ackroyd, Raghu Kalluri, Jianhua Zhang, Shan Jiang, Denise J. Spring, Y. Alan Wang and Ronald A. DePinho Abstract Oncogenic KRAS (KRAS*) is

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A Single-Dose HPV Vaccine Would Have a Big Impact on Cancer Prevention

As the father of three teenagers, as a son whose father lost his battle with cancer, and as a physician-scientist who specialized in cancer research for more than four decades, I was heartened by the recent and welcome news of continued declines in US cancer mortality rates, driven by continued reductions in tobacco use, increased

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Immunometabolism in Pancreatic Cancer

Oncogenic Kras driven metabolic reprogramming in pancreas cancer cells utilizes cytokines from the tumor microenvironment. Authors: Prasenjit Dey, Jun Li, Jianhua Zhang, Surendra Chaurasiya, Anders Strom, Huamin Wang, Wen-Ting Liao, Frederick Cavallaro, Parker Denz, Vincent P. Bernard, Er-Yen Yen, Giannicola Genovese, Prateek Gulhati, Jielin Liu, Deepavali Chakravarti, Pingna Deng, Tingxin Zhang, Federica Carbone, Edward Chang,

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