We held a call with Ron DePinho MD, past president of the University of Texas MD Anderson Cancer Center, to discuss the COVID-19 pandemic and his perspective. Although the growing number of cases, the impact on those infected, and the steps being taken to slow the virus’s spread are causing immeasurable burden, Dr. DePinho expressed […]
COVID-19 and the Life Sciences Revolution Read More »
A great video on the Coronavirus produced by Kurzgesagt – In a Nutshell, a Munich-based YouTube channel and design studio. See video
Covid-19 Explained & What You Should Do Read More »
Self-isolation and social distancing NOW is critical … Science article reports that, prior to lockdown in China, >85% of CV infections were asymptomatic or mild. The transmission rate of these infections was estimated to be 55% of documented infections. Science article
As the father of three teenagers, as a son whose father lost his battle with cancer, and as a physician-scientist who specialized in cancer research for more than four decades, I was heartened by the recent and welcome news of continued declines in US cancer mortality rates, driven by continued reductions in tobacco use, increased
A Single-Dose HPV Vaccine Would Have a Big Impact on Cancer Prevention Read More »
Just in – our paper was selected as the COVER for Cancer Discovery. Glioblastoma (GBM) is a lethal brain tumor containing a subpopulation of glioma stem cells (GSC). Pan-cancer analyses have revealed that stemness of cancer cells correlates positively with immunosuppressive pathways in many solid tumors, including GBM, prompting us to conduct a gain-of-function screen
Oncogenic Kras driven metabolic reprogramming in pancreas cancer cells utilizes cytokines from the tumor microenvironment. Authors: Prasenjit Dey, Jun Li, Jianhua Zhang, Surendra Chaurasiya, Anders Strom, Huamin Wang, Wen-Ting Liao, Frederick Cavallaro, Parker Denz, Vincent P. Bernard, Er-Yen Yen, Giannicola Genovese, Prateek Gulhati, Jielin Liu, Deepavali Chakravarti, Pingna Deng, Tingxin Zhang, Federica Carbone, Edward Chang,
Immunometabolism in Pancreatic Cancer Read More »
2019 was a notable one for the cancer research community in its quest to prevent, detect and treat cancers. Below is my ‘top ten’ list of recent notable advances: #10: Necroptosis: Researchers found that when cells undergoing necroptosis (a type of programmed cell death) were injected into tumors in mice, they helped to initiate an
2019 Highlights: Top Ten Advances Read More »
Glioblastoma multiforme, colorectal cancer, and pancreatic ductal adenocarcinoma represent some of the most difficult-to-treat cancers and collectively cause more than 114,000 deaths each year in the United States. A trio of recently published basic research studies in these cancers have found potential therapeutic targets that may help propel the launch of clinical trials in the
There has never been a more opportune time for those in academia and healthcare to accelerate discoveries into advances for treating patients. However, many discoveries often remain trapped in medical journals instead of being fully leveraged to save lives and reduce suffering. To make an impact, academic leaders must encourage and embrace an entrepreneurial spirit
Leadership Series 3: Achieving Success as a Biotech Leader Read More »
The delay in implementing comprehensive regulations for e-cigarettes has contributed to a growing crisis of vaping-related illnesses and deaths across the U.S. and poses particular risks to young adults. The big picture: E-cigarette use by American teenagers has surged, and the dangers are heightened by unsafe black market vaping devices and THC cartridges. But a
Regulatory Gaps and Youth Vaping Read More »
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